
4-Hydroxybenzyl alcohol
CAS No. 623-05-2
4-Hydroxybenzyl alcohol( —— )
Catalog No. M18916 CAS No. 623-05-2
4-Hydroxybenzyl alcohol exhibits beneficial effects in cerebral ischemic injury, has neuroprotective effect through upregulation of Nrf2, Prdx6, and PDI expression via the PI3K/Akt pathway.
Purity : >98% (HPLC)






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Biological Information
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Product Name4-Hydroxybenzyl alcohol
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NoteResearch use only, not for human use.
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Brief Description4-Hydroxybenzyl alcohol exhibits beneficial effects in cerebral ischemic injury, has neuroprotective effect through upregulation of Nrf2, Prdx6, and PDI expression via the PI3K/Akt pathway.
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Description4-Hydroxybenzyl alcohol exhibits beneficial effects in cerebral ischemic injury, has neuroprotective effect through upregulation of Nrf2, Prdx6, and PDI expression via the PI3K/Akt pathway. 4-Hydroxybenzyl alcohol inhibit the development of new blood vessels by targeting multiple mechanisms of the angiogenic process, may as a promising candidate for the establishment of anti-angiogenic treatment strategies in cancer therapy.
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In Vitro4-Hydroxybenzyl alcohol inhibits proliferation of eEND2 cells and suppresses the migration of eEND2 cells, accompanied by inhibition of actin filament reorganization.4-Hydroxybenzyl alcohol induces apoptotic death of tumor cells.
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In Vivo4-Hydroxybenzyl alcohol possesses antiangiogenic, anti-inflammatory and anti-nociceptive activity possibly via its down-regulating activity on NO production. 4-Hydroxybenzyl alcohol (200 mg/kg) efficiently inhibits growth and angiogenesis of developing tumors.4-Hydroxybenzyl alcohol ameliorates ischemic injury induced by transient focal cerebral ischemia in rats, and this neuroprotective effect may be partly related to attenuate apoptosis pathway.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research AreaOthers-Field
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Indication——
Chemical Information
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CAS Number623-05-2
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Formula Weight124.14
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Molecular FormulaC7H8O2
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Purity>98% (HPLC)
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SolubilityDMSO : 100 mg/mL; 805.54 mM
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SMILESC1=CC(=CC=C1CO)O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Laschke MW,et al.4-hydroxybenzyl alcohol: a novel inhibitor of tumor angiogenesis and growth. 2013 Jul 19;93(1):44-50.
molnova catalog



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